One way to send e-mail is to use Microsoft's CDONTS component NewMail. See Microsoft's documentation of the NewMail object for details.
Here is a short example to help you get started:
Set objNewMail = CreateObject("CDONTS.NewMail")
objNewMail.Send "firstname.lastname@example.org", "email@example.com", "Hello", "I sent this in 3 statements!", 0 ' low importance
Set objNewMail = Nothing ' can NOT reuse it for another message
Look also at your cgi-bin directory for other examples that implement this component (SimpleMail.asp, SendMail.asp).